Structural change of macular capillaries after vitrectomy
Purpose. To determine the size of the superficial foveal avascular zone (FAZ) by optical coherence tomographic angiography (OCTA) before and after surgery for an idiopathic macular hole (MH).
Material and methods. Sixteen eyes of 16 patients with an idiopathic MH were studied. Pars plana vitrectomy was performed with internal limiting membrane (ILM) peeling. The foveal retinal vasculature was examined by OCTA, and the area of the superficial FAZ was determined before, and at 1 and 3 months after the surgery. The central foveal thickness (CFT) was measured to determine the relationship between the size of the superficial FAZ and foveal shape. The unaffected fellow eyes were used as controls.
Results. The average preoperative superficial FAZ area was 0.45±0.14 mm2 which was significantly reduced to 0.23±0.08 mm2 at 1 month (P <0.001) and 0.25±0.08 mm2 at 3 months postoperatively (P<0.001). The size was smaller than that of the control eyes (0.36±0.12 mm2, P=0.003). There was a significant inverse correlation between the area of the postoperative superficial FAZ and the CFT (r=-0.589, P=0.016). The correlations between the visual acuity and the area of the superficial FAZ at 1 and 3 months postoperatively were not significant (P =0.369 and =0.285).
Conclusions. The significant decrease in the superficial FAZ after the MH surgery indicates that there was a centripetal movement of the foveal tissue postoperatively.
Key words: vitrectomy, macular hole, angiography.
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